// Detailed ClinVar per-gene information.

syntax = "proto3";

package annonars.clinvar.per_gene;

import "annonars/clinvar_data/class_by_freq.proto";
import "annonars/clinvar_data/extracted_vars.proto";
import "annonars/clinvar_data/gene_impact.proto";

// Extracted variants per release.
message ExtractedVariantsPerRelease {
    // Release version.
    optional string release = 1;
    // Variants per gene.
    repeated clinvar_data.extracted_vars.ExtractedVcvRecord variants = 2;
}

// ClinVar detailed information per gene.
message ClinvarPerGeneRecord {
    // Counts of variants per impact
    optional clinvar_data.gene_impact.GeneImpactCounts per_impact_counts = 1;
    // Counts of variants per impact / frequency
    optional clinvar_data.class_by_freq.GeneCoarseClinsigFrequencyCounts per_freq_counts = 2;
    // Variants for the given gene.
    repeated ExtractedVariantsPerRelease per_release_vars = 3;
}