// Genomic region annotation with ClinGen information.

syntax = "proto3";

package annonars.regions.clingen;

import "annonars/genes/base.proto";

// Dosage pathogenicity region annotation.
message Region {
    // ISCA ID
    string isca_id = 1;
    // ISCA Region Name
    string isca_region_name = 2;
    // Genomic locaion.
    string genomic_location = 3;
    // Haploinsufficiency score.
    annonars.genes.base.ClingenDosageScore haploinsufficiency_score = 4;
    // Triplosensitivity score.
    annonars.genes.base.ClingenDosageScore triplosensitivity_score = 5;
    // Haploinsufficiency Disease ID.
    optional string haploinsufficiency_disease_id = 6;
    // Haploinsufficiency Disease ID.
    optional string triplosensitivity_disease_id = 7;
}