description: |
  A ten population model of out-of-Africa, including two pulses of
  Denisovan admixture into Papuans, and several pulses of Neandertal
  admixture into non-Africans.
  Most parameters are from Jacobs et al. (2019), Table S5 and Figure S5.
  This model is an extension of one from Malaspinas et al. (2016), thus
  some parameters are inherited from there.
time_units: generations
doi:
- https://doi.org/10.1016/j.cell.2019.02.035
- https://doi.org/10.1038/nature18299

demes:
- name: YRI
  epochs:
  - {end_time: 20225.0, start_size: 32671.0}
  - {end_time: 2218.0, start_size: 41563.0}
  - {end_time: 0, start_size: 48433.0}
- name: DenA
  ancestors: [YRI]
  start_time: 20225.0
  epochs:
  - {end_time: 15090.0, start_size: 13249.0}
  - {end_time: 12500.0, start_size: 100.0}
  - {end_time: 9750.0, start_size: 100.0}
  - {end_time: 0, start_size: 5083.0}
- name: NeaA
  ancestors: [DenA]
  start_time: 15090.0
  epochs:
  - {end_time: 3375.0, start_size: 13249.0}
  - {end_time: 0, start_size: 826.0}
- name: Den2
  ancestors: [DenA]
  start_time: 12500.0
  epochs:
  - start_size: 13249.0
- name: Den1
  ancestors: [DenA]
  start_time: 9750.0
  epochs:
  - start_size: 13249.0
- name: Nea1
  ancestors: [NeaA]
  start_time: 3375.0
  epochs:
  - start_size: 13249.0
- name: Ghost
  ancestors: [YRI]
  start_time: 2218.0
  epochs:
  - {end_time: 2119.0, start_size: 1394.0}
  - {end_time: 0, start_size: 8516.0}
- name: Papuan
  ancestors: [Ghost]
  start_time: 1784.0
  epochs:
  - {end_time: 1685.0, start_size: 243.0}
  - {end_time: 0, start_size: 8834.0}
- name: CHB
  ancestors: [Ghost]
  start_time: 1758.0
  epochs:
  - {end_time: 1659.0, start_size: 2231.0}
  - {end_time: 1293.0, start_size: 12971.0}
  - {end_time: 0, start_size: 9025.0}
- name: CEU
  ancestors: [CHB]
  start_time: 1293.0
  epochs:
  - start_size: 6962.0

migrations:
- {demes: [YRI, Ghost], rate: 0.000179, start_time: 1659.0}
- {demes: [CHB, Papuan], rate: 0.000572, start_time: 1659.0, end_time: 1293.0}
- {demes: [CHB, Papuan], rate: 5.72e-05, start_time: 1293.0}
- {demes: [CHB, Ghost], rate: 0.000442, start_time: 1659.0, end_time: 1293.0}
- {demes: [CEU, CHB], rate: 3.14e-05}
- {demes: [CEU, Ghost], rate: 0.000442}

pulses:
- {sources: [Nea1], dest: Ghost, time: 1853.0, proportions: [0.024]}
- {sources: [Den2], dest: Papuan, time: 1575.8620689655172, proportions: [0.018]}
- {sources: [Nea1], dest: CHB, time: 1566.0, proportions: [0.011]}
- {sources: [Nea1], dest: Papuan, time: 1412.0, proportions: [0.002]}
- {sources: [Den1], dest: Papuan, time: 1027.5862068965516, proportions: [0.022]}
- {sources: [Nea1], dest: CHB, time: 883.0, proportions: [0.002]}