LOCUS BGC0002746 38658 bp DNA linear CON 24-APR-2019 DEFINITION Dendrothele bispora CBS 962.96 unplaced genomic scaffold K435scaffold_621, whole genome shotgun sequence. ACCESSION BGC0002746 VERSION BGC0002746 KEYWORDS . SOURCE Dendrothele bispora CBS 962.96 ORGANISM Dendrothele bispora CBS 962.96 Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes; Agaricomycetidae; Agaricales; Agaricales incertae sedis; Dendrothele. COMMENT URL -- http://genome.jgi.doe.gov/Denbi1 JGI Project ID: 1016303 The DNA was provided by Lazlo Nagy (lnagy@clarku.edu) The strain is available from CBS-KNAW culture collection Contacts: Lazlo Nagy (lnagy@clarku.edu) Assembly and annotation done by JGI. The JGI and collaborators endorse the principles for the distribution and use of large scale sequencing data adopted by the larger genome sequencing community and urge users of this data to follow them. It is our intention to publish the work of this project in a timely fashion and we welcome collaborative interaction on the project and analysis. (http://www.genome.gov/page.cfm?pageID=10506376). ##antiSMASH-Data-START## Version :: False Run date :: 2022-10-08 16:58:47 NOTE: This is a single region extracted from a larger record! Orig. start :: 8357 Orig. end :: 47015 ##antiSMASH-Data-END## FEATURES Location/Qualifiers subregion 1..38658 /aStool="mibig" /contig_edge="False" /label="RiPP" /subregion_number="1" /tool="antismash" region 1..38658 /contig_edge="False" /product="unknown" /region_number="1" /subregion_numbers="1" /tool="antismash" mRNA <849..>1056 /locus_tag="K435DRAFT_871160" /product="hypothetical protein" gene <849..>1056 /locus_tag="K435DRAFT_871160" CDS 849..>1056 /codon_start=1 /db_xref="JGIDB:Denbi1_871160" /locus_tag="K435DRAFT_871160" /product="hypothetical protein" /protein_id="THU83547.1" /transl_table=1 /translation="MSSEGISTGDTEDTSVKGDIEGEGSTENRAVLESSDSEVLNLFDP LELKSDSGDEERLGRFPKDFVEGV" mRNA complement(join(<1873..2099,2158..2240,2289..2385, 2421..>2477)) /locus_tag="K435DRAFT_971507" /product="hypothetical protein" gene complement(<1873..>2477) /locus_tag="K435DRAFT_971507" CDS complement(join(<1875..2099,2158..2240,2289..2385, 2421..2477)) /codon_start=1 /db_xref="InterPro:IPR000626" /db_xref="JGIDB:Denbi1_971507" /locus_tag="K435DRAFT_971507" /note="expressed protein; GO_process: GO:6464 - protein modification process" /product="hypothetical protein" /protein_id="THU83548.1" /transl_table=1 /translation="MKVTIKTLQADSYQASSAFIDAEPTDSIGVIKSKIEESQGFSAHL QKIVFSGELLKDDDRTLESYGFSEDRYLILMVNQKNKTKAPVLGVPSTSNSILGHGDGS NAAGPRSITTPSVKTSTVFPATAGPSKYPGALVPYSAQSSTPPSAVLNRP" mRNA join(6357..6429,6492..6590,6651..7021,7075..7142, 7210..7610) /locus_tag="K435DRAFT_784133" /product="hypothetical protein" gene 6357..7610 /locus_tag="K435DRAFT_784133" CDS join(6385..6429,6492..6590,6651..7021,7075..7142, 7210..7556) /codon_start=1 /db_xref="JGIDB:Denbi1_784133" /locus_tag="K435DRAFT_784133" /note="expressed protein" /product="hypothetical protein" /protein_id="THU83549.1" /transl_table=1 /translation="METQNLDLSAISAPNNSVRLHQPVLPNTSYEYQQHMSGSHEQSQT QNTAYTVDQTVNHASFSLPFYDKFLGPGPPPVSSVPIPSGPQLYPLQDQSSSLSDNHNV SLQNPELSSRRALEGSMHLIQNHPIPDELNLHQLENTNSFQQPLVNLQSGGTHTSAFVL ETGQCNTSKAPSELRVDEMRVKIKEQFLSMLKSHNIDTGDKLPWRNLLKILQERKCQFE NWPEGIPHPHTQNGIEKAPQKEIKALYKALLDKERPLRICRIDRGSGGADLRFILQDPP GSGSNAKRNRDEQGGEIEERESNRRRMD" mRNA join(9035..9150,9204..9753,9826..9833) /locus_tag="K435DRAFT_425274" /product="hypothetical protein" gene 9035..9833 /locus_tag="K435DRAFT_425274" CDS 9219..9599 /codon_start=1 /db_xref="JGIDB:Denbi1_425274" /locus_tag="K435DRAFT_425274" /note="expressed protein" /product="hypothetical protein" /protein_id="THU83550.1" /transl_table=1 /translation="MSIKENVPGVHSGNIAWLQLTETDLAAESWSCYTNARNVTSSNPS LREIDRKLDLGVSRLKLTRERSMPHNIISLFLQTSLNGFPLEATARRYTCQLLRVDTST SLAGILIHLFESVVDIVCKYLL" mRNA join(10156..10180,10238..10446,10503..10694,10760..10789) /locus_tag="K435DRAFT_425234" /product="hypothetical protein" gene 10156..10789 /locus_tag="K435DRAFT_425234" CDS join(10346..10446,10503..10635) /codon_start=1 /db_xref="JGIDB:Denbi1_425234" /locus_tag="K435DRAFT_425234" /note="expressed protein" /product="hypothetical protein" /protein_id="THU83551.1" /transl_table=1 /translation="MDDQQLENPDETGDKSLADSISRYKIAIIVVVIGIILIIVIAYLI HRPPTTLLATYARWNRLMREYAGLAWRSNLSY" mRNA complement(join(10834..11276,11347..11443)) /locus_tag="K435DRAFT_784134" /product="hypothetical protein" gene complement(10834..11443) /locus_tag="K435DRAFT_784134" CDS complement(join(10879..11276,11347..11374)) /codon_start=1 /db_xref="JGIDB:Denbi1_784134" /locus_tag="K435DRAFT_784134" /note="expressed protein" /product="hypothetical protein" /protein_id="THU83552.1" /transl_table=1 /translation="MVSTRGPPAGIIHLDRLPSLRRLGLTAVLSGLQDNTTQNLISGLA QFFEISNTNTTEITHLAFGFSFSTTSLVFNPFRVPWWRLDTALAALPTLRWVGVQVIDR RCETSIIIPEDSVNMFPMLSEKGLLHWSTGRLEFPAM" mRNA join(<12926..12945,13129..13417,13478..13622,13681..13751, 13801..13850,13901..13951,14016..14043,14095..14207, 14273..14626,14686..14776,14834..14862,14913..15059, 15136..15172,15226..15343,15407..15492,15553..15600, 15655..15689,15742..15839,15908..16005,16069..16109, 16169..>16250) /locus_tag="K435DRAFT_871165" /product="hypothetical protein" gene <12926..>16250 /locus_tag="K435DRAFT_871165" CDS join(12926..12945,13129..13417,13478..13622,13681..13751, 13801..13850,13901..13951,14016..14043,14095..14207, 14273..14626,14686..14776,14834..14862,14913..15059, 15136..15172,15226..15343,15407..15492,15553..15600, 15655..15689,15742..15839,15908..16005,16069..16109, 16169..16250) /codon_start=1 /db_xref="InterPro:IPR001375" /db_xref="InterPro:IPR004106" /db_xref="JGIDB:Denbi1_871165" /gene_functions="biosynthetic-additional (rule-based-clusters) Peptidase_S9" /gene_kind="biosynthetic-additional" /locus_tag="K435DRAFT_871165" /note="expressed protein; GO_function: GO:8236; serine-type endopeptidase activity - serine-type peptidase activity [GO Ref 4252]; GO_process: GO:6508 - proteolysis" /product="hypothetical protein" /protein_id="THU83553.1" /sec_met_domain="Peptidase_S9 (E-value: 8.6e-52, bitscore: 165.8, seeds: 64, tool: rule-based-clusters)" /transl_table=1 /translation="MKARKLKEVWLETLKQSWNYKRFTVPRHESDDHIYFEYNDGLQSQ LSLHRVKVGDEDTILTESGPGGELFFDPNMISLDGNASLTGFIMSPCGKYWAYGVSEHG SDWMTIYVRETSSPHVPSQERGKDPGRMDDEVRHSRFFIVSWTGDSKGFFYSKYPPEEN EGKGNAPAKNCIVYYHRLGEKQENDTLVHKDSGHPFWLWSLQTTPSGRYALLAASRDAS HTQLAKIADIHDNDIGASMKWINLHDSWEARFSIIGDDDSKIYFMTNLQAPNYKVAIFD ACHPSPDADLTTLVAEDPNALLIAASIHAKDKLALVYLRDARHEIHVHDLVTGRLLRRI LGDLVGQFMVTGRRADNDMFIFYSGFTSPGTVYRYKFDDERDTCSLFRAIRIPGLDLDK FVTESVFYPSKDGTSIHMFITRPKDVLLDGTAPVLQYGYGGFALAMLPTFSVSTLLFCK IYRAIGGSEYGESWHRAGMLGNKQNVFDDLNAATEWLVANKYANKDRVAIRGGSNGGVL TTACANQAPGLYRCVITIGGIIDMLRFPKFTFGALWCSEYGDPEDPEAFDFIYKYSPYH NIPSGETVMPAMLFFTAAYDDRVSPLHTFKHVAALQHSFPHGPNPILMRVDMNSGHYAG KSTQKMLEETADEYSFIGKSMGLTMQVENKSDSNRWSCVVN" CDS complement(join(16931..17163,17242..17676,17741..18083, 18137..18225,18289..18394,18454..18558,18611..18784)) /codon_start=1 /db_xref="InterPro:IPR001128" /db_xref="JGIDB:Denbi1_971512" /gene_functions="biosynthetic-additional (rule-based-clusters) p450" /gene_functions="biosynthetic-additional (smcogs) SMCOG1034:cytochrome P450 (Score: 126.4; E-value: 2.4e-38)" /gene_kind="biosynthetic-additional" /locus_tag="K435DRAFT_971512" /note="GO_function: GO:4497; iron ion binding - monooxygenase activity [Evidence 20037] [GO Ref 5506; heme binding]" /product="cytochrome P450" /protein_id="THU83554.1" /sec_met_domain="p450 (E-value: 1.7e-35, bitscore: 112.7, seeds: 50, tool: rule-based-clusters)" /transl_table=1 /translation="MGVIIATFIGIALLQVAVLASRKFKEFYIDVLAVAYGHDFMTSSF RTGENTFHFHLFKNFVIGVRGQEARKMFFEEKSLSSSEGYRMFSKAVPTPELSATQLLF AEEEHSIHFKKQLGILLGKNRYTEIIATMLGDLQRITAAWGEEGTMDPFDHINDITFLV TLHMITSHEFVSDHAFLSRFQNHFFTQLKNNTPGMIFFPWLYRSAQRDKENSVMVLFSA LSEHIETRKGSSGVSSEPIDLLLAHGMDTQGIIQFILGFLFGGVFNITKATSWILIYTS LHPQWKTSLRSEIKSMLSHLSIDTSEPLYIRLSQVPIKAWEESMPTLDLVISETLRLIM NQTVLRRNVGEALQIPGGKDDHVVSLPRGAFVVYNHADAHLNPEVYTDPWRFDPQRHTN LSSPGHQKNSYEFLGWGAGRHRCAGVKIAKLAIKTIVSLFVMNYEYDAITTRRKTHSST VPIPDYNKVNGVSTMAFFESIDPNGKLIDLVNPGAS" mRNA complement(join(<16931..17163,17242..17676,17741..18083, 18137..18225,18289..18394,18454..18558,18611..18860)) /locus_tag="K435DRAFT_971512" /product="cytochrome P450" gene complement(<16931..18860) /locus_tag="K435DRAFT_971512" mRNA join(19014..19135,19189..19895,19950..19977,20043..20528) /locus_tag="K435DRAFT_733899" /product="hypothetical protein" gene 19014..20528 /locus_tag="K435DRAFT_733899" CDS join(19222..19895,19950..19977,20043..20453) /codon_start=1 /db_xref="JGIDB:Denbi1_733899" /locus_tag="K435DRAFT_733899" /note="expressed protein" /product="hypothetical protein" /protein_id="THU83555.1" /transl_table=1 /translation="MNRLFALAALSKSFSTFGMVVRPSPYRWLFLLPVIAINGYCYFST FSEDSIRVNILIETLMASDYILLTDIQREFRQIGQQEPIYNLGIWARFKWTVQLLFSPR GVGWTHEMKSIIPSHPNLTRLEFLRSRFISLIMALIGNDIAFILTSIDPGFSEHAPPFD EQPVVWRFWATGLFFFRLKSAINVYLLLVALLLVGTGLSEPDVWPDFFGKLSDAYTVRR WWGRVWHQQLRRIFSSHGKFLSQRVCGFRTGTLASSYTRLYLAFFLSGLIHITSLDPRP IRFFLSQAVVITFEDSVIAAANRVGFKRSQAIIRVLGYFWVYFVLSFTFGPWLDSMNAT GVGGYDGTLVLGRYRDSWWLKGLLTQLDRR" mRNA complement(join(20580..21425,21492..21809,21874..22159)) /locus_tag="K435DRAFT_765759" /product="tetrapyrrole methylase" gene complement(20580..22159) /locus_tag="K435DRAFT_765759" CDS complement(join(20733..21425,21492..21809,21874..22116)) /codon_start=1 /db_xref="InterPro:IPR000878" /db_xref="JGIDB:Denbi1_765759" /gene_functions="biosynthetic-additional (rule-based-clusters) TP_methylase" /gene_kind="biosynthetic-additional" /locus_tag="K435DRAFT_765759" /note="GO_function: GO:8168 - methyltransferase activity; GO_process: GO:8152 - metabolic process" /product="tetrapyrrole methylase" /protein_id="THU83556.1" /sec_met_domain="TP_methylase (E-value: 1.7e-19, bitscore: 60.7, seeds: 87, tool: rule-based-clusters)" /transl_table=1 /translation="MESSTQTKPGSLIVVGTGIESIGQMTLQALSYIEAASKVFYCVID PATEAFILTKNKNCVDLYQYYDNGKSRMDTYTQMAELMLKEVRNGLDVVGVFYGHPGVF VNPSHRALAIARSEGYQARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRERPVN VHSHLILFQVGCVGIADFNFSGFDNSKFTILVDRLEQEYGPDHTVVHYIAAMMPHQDPV TDKFTIGQLREPEIAKRVGGVSTFYIPPKARKDINTDIIRLLEFLPAGKVPDKHTQIYP PNQWEPDVPTLPPYGQNEQAAITRLEAHAPPEEYQPLATSKAMTDVMTKLALDPKALAE YKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMPSSLLEAASQSVEEASMNGFP WVIVTGIVGVIGSVVSSA" mRNA join(24006..24388,24442..24546,24598..24703,24760..25127) /locus_tag="K435DRAFT_425347" /product="hypothetical protein" gene 24006..25127 /locus_tag="K435DRAFT_425347" CDS join(24104..24388,24442..24546,24598..24703,24760..24887) /codon_start=1 /db_xref="JGIDB:Denbi1_425347" /locus_tag="K435DRAFT_425347" /note="expressed protein" /product="hypothetical protein" /protein_id="THU83557.1" /transl_table=1 /translation="MSSHPLSYHLVSPYIKADFNSTIISKETVTTWVQYSLGWLQLSVA FILVATVAVFVKNKVQQIWITCLFFSRAYDLITSKLRVSSSNAFSFLVFDLPITAVKGK AARKSFFEDRNLSNAEGYRIFGGPNAISKVDENHVHPDKDEHLTRFMLRITDLVQRDRY TDAMPALFDAVGDLMATWGNQGIMDPFQNIYDVSLYYPSIPPPK" mRNA join(<24927..25223,25303..25702,25760..25911,25976..>26035) /locus_tag="K435DRAFT_822935" /product="cytochrome P450" gene <24927..>26035 /locus_tag="K435DRAFT_822935" CDS join(24927..25223,25303..25702,25760..25911,25976..26035) /codon_start=1 /db_xref="InterPro:IPR001128" /db_xref="JGIDB:Denbi1_822935" /gene_functions="biosynthetic-additional (rule-based-clusters) p450" /gene_functions="biosynthetic-additional (smcogs) SMCOG1034:cytochrome P450 (Score: 92.9; E-value: 3.7e-28)" /gene_kind="biosynthetic-additional" /locus_tag="K435DRAFT_822935" /note="GO_function: GO:4497; iron ion binding - monooxygenase activity [Evidence 20037] [GO Ref 5506; heme binding]" /product="cytochrome P450" /protein_id="THU83558.1" /sec_met_domain="p450 (E-value: 9.7e-26, bitscore: 80.5, seeds: 50, tool: rule-based-clusters)" /transl_table=1 /translation="MATCREFSSDLATLSEFKAHFLNVETNTHPNSAVFPWLYHSVRRS KEASVKALHSTLAHFVEKRRQATVPNSDAIDILLAQNASTPDIVLLSLGSIFAGFLIFI FIHPEWKTAILAELKPLVSQYGNAADPVHRQPAMIPSSVWDSSMPTIDLVMRETIRLVI NHTALRRNVGESFDMPGGVGEIKRGSFLAYSLADAHLDPGVYSRPHLFDPERFRPDREE DPSAFLGFGAGRHRCLASKLARLEIKSIVALFLMTYDYEVVDANGNFLQTIPAPDYNDV QLARPKDMECFLRFKRMENHN" mRNA join(26598..27354,27414..27441,27499..27974) /locus_tag="K435DRAFT_784138" /product="hypothetical protein" gene 26598..27974 /locus_tag="K435DRAFT_784138" CDS join(26681..27354,27414..27441,27499..27888) /codon_start=1 /db_xref="JGIDB:Denbi1_784138" /locus_tag="K435DRAFT_784138" /note="expressed protein" /product="hypothetical protein" /protein_id="THU83559.1" /transl_table=1 /translation="MNYLFVSASLTKCIILIGLVVRSSPYRWLLWVPVAAVNTYCYLST DSENSLRVQVLLDTLTASDYILLTDVQREFRQVGQREPISSAGIWPRFKWALQLWISPR GVGWNFEPKSSLPPHPNLTKLEFLRSRFISLALALIGNDIAFILASSDPGFSKHAPAFH KQPVTWRLYATALFFFRTRSALTVNYLMISLLCVGTGMTEPSSWPDLFGKWGHSYTLRR FWGVTWHQQLRRIFSSHGRFLAHRVFGFPSGSIASSYTQLYVAFFLSSIIHVLSFDFRP FRFFLLQAVVITFEDTIILIGREYRVQKKLTIPFRLLGYLWVYWTLTLTLGPWFDTMNV AGVNEYNGAYVLGFLRDWLLSED" mRNA join(28862..29087,29148..29195,29250..29278,29332..29572) /locus_tag="K435DRAFT_971516" /product="hypothetical protein" gene 28862..29572 /locus_tag="K435DRAFT_971516" CDS join(28905..29087,29148..29195,29250..29278,29332..29434) /codon_start=1 /db_xref="JGIDB:Denbi1_971516" /locus_tag="K435DRAFT_971516" /note="expressed protein" /product="hypothetical protein" /protein_id="THU83560.1" /transl_table=1 /translation="MTDKVKIVRDYHDLLNAGQIAQANAHLAHNLTANFSVGGPQLNKE EVGNVQQGVQNALNTTTLITEAKEVDGKVVVVGKSLLKLKVEEVPFKAVYEFNGNQIGA VKFETDPSFQVKAFSI" mRNA complement(join(29732..29974,30031..30167,30246..30353, 30410..30583,30635..30754,30809..30932,30993..31089, 31150..31233,31298..31457,31537..31668,31719..31823, 31900..>32112)) /locus_tag="K435DRAFT_971517" /product="cytochrome P450" gene complement(29732..>32112) /locus_tag="K435DRAFT_971517" CDS complement(join(29800..29974,30031..30167,30246..30353, 30410..30583,30635..30754,30809..30932,30993..31089, 31150..31233,31298..31457,31537..31668,31719..31823, 31900..32112)) /codon_start=1 /db_xref="InterPro:IPR001128" /db_xref="JGIDB:Denbi1_971517" /gene_functions="biosynthetic-additional (rule-based-clusters) p450" /gene_functions="biosynthetic-additional (smcogs) SMCOG1034:cytochrome P450 (Score: 121.1; E-value: 9.7e-37)" /gene_kind="biosynthetic-additional" /locus_tag="K435DRAFT_971517" /note="GO_function: GO:4497; iron ion binding - monooxygenase activity [Evidence 20037] [GO Ref 5506; heme binding]" /product="cytochrome P450" /protein_id="THU83561.1" /sec_met_domain="p450 (E-value: 1.1e-41, bitscore: 133.1, seeds: 50, tool: rule-based-clusters)" /transl_table=1 /translation="MMRKSEQIPVESQLRMVQQFTEKIAIDTSLIPALWLSSNGVEDTR ILPFTLCASTLVQLVSLSASSSLSFSLNIPTIGGEGLLDSYVGAYKFLFGTRDLIQEGY DKHYGKAFRIPMLSGWLVLVTGPRMIEEVRAASESGLSSRAALFKESLQTDYTFSPEYL LDPYHFQFVQTSLVRDLGVRIAEIKDEIATVFAELIPPTNDWTRLGGCLTGQQLAFSST TRLLVGLRLCRDPEYKALNDHWPDTLATAAIIISQVPKVMKPLATRLLFFYRDTLAEAM KHVGPTLKERLEKQKQFGEEELDTSQDDLLNWLLEKAPASEKSLEAITKRLMAIHFVAY RPLSLAITQVLYDLAAQSSYIPELRSEVEALVDGQVITKAGLDKMYKLDSFVKESLRLH GSAKVTMSRKVMKDFTFSDGTTIPAGNTLGACGFSIHHDERNYPNPEEFDGFRHFRKHE AENEPVRYQLASLSADYVVFGVGRHACPGRFLVAAILKTMLAHVLLTYDVKLETEGVRP LDEWQGMLAAVPHQTAGVMFRRRGS" CDS join(32411..32503,32564..32671,32719..32847,32906..33065, 33119..33202,33265..33361,33417..33546,33604..33717, 33772..33946,34000..34106,34162..34298,34358..34538) /codon_start=1 /db_xref="InterPro:IPR001128" /db_xref="JGIDB:Denbi1_843994" /gene_functions="biosynthetic-additional (rule-based-clusters) p450" /gene_functions="biosynthetic-additional (smcogs) SMCOG1034:cytochrome P450 (Score: 134.3; E-value: 9.9e-41)" /gene_kind="biosynthetic-additional" /locus_tag="K435DRAFT_843994" /note="GO_function: GO:4497; iron ion binding - monooxygenase activity [Evidence 20037] [GO Ref 5506; heme binding]" /product="cytochrome P450" /protein_id="THU83562.1" /sec_met_domain="p450 (E-value: 9.5e-47, bitscore: 149.8, seeds: 50, tool: rule-based-clusters)" /transl_table=1 /translation="MSSSTWLTLAVALISLLLARSVIDERIIRSKYKNVISVGPSGMFG TLIGTFQLLLGYRDFIQEGYEKHYGKLFRIPTLFTMTFVVTGHDLLEDVRKASDDQLSL YGSIKEGMQTDYTMEPHILDNPYHFRFVHLSLTRDLGGRFPELREEVITAFSELVPPTD DWTSFPAWLTGKSIVLRVTNKLFVGPPLCHDLDYNDINDTYSDALVKTALIVGLTPDFL KPIVASTLYFYIPKTLKRAMKHVAPLVQERLEKERTFGKDWPGKPNDLLSWLMEKAPES DKSVRAITIRLLATMFAAYRPASMALTQALFDLATYPSYIPELRAEIEPIVKEKGITKE SINKMYKLDSFIKESLRLRGGGKSSMPRKVLKDFTFSDGNTVYTGSTIIATGYAIHHDA RHYPDPDEFDGFRFARLREAENDPVRYQMVSVGPTYMMFGNGRHACPGRFLVSALLKTM LAHVLMTYDVKLEQDDGVRPPDKWFTFAPAPNETASLMFRKRANLA" mRNA join(<32411..32503,32564..32671,32719..32847,32906..33065, 33119..33202,33265..33361,33417..33546,33604..33717, 33772..33946,34000..34106,34162..34298,34358..34648) /locus_tag="K435DRAFT_843994" /product="cytochrome P450" gene <32411..34648 /locus_tag="K435DRAFT_843994" mRNA complement(join(36323..36694,36761..37112,37177..37401, 37462..37543,37624..37881)) /locus_tag="K435DRAFT_765773" /product="arylalcohol dehydrogenase" gene complement(36323..37881) /locus_tag="K435DRAFT_765773" CDS complement(join(36408..36694,36761..37112,37177..37401, 37462..37543,37624..37856)) /codon_start=1 /db_xref="InterPro:IPR001395" /db_xref="JGIDB:Denbi1_765773" /gene_functions="biosynthetic-additional (smcogs) SMCOG1039:aldo/keto reductase family oxidoreductase (Score: 261.1; E-value: 2e-79)" /gene_kind="biosynthetic-additional" /locus_tag="K435DRAFT_765773" /note="GO_function: GO:16491 - oxidoreductase activity" /product="arylalcohol dehydrogenase" /protein_id="THU83563.1" /transl_table=1 /translation="MSAFLPPEAPPSKLGIYRVLSPKAGVRVSPLVLGGASIGSGDSGW KSVWGDMDEAKAYRLLDKFYELGGNFIDTANNYQEETSEQIIGKWAEERRIRDQLFIAT KYTSGYKKNDTTVKQKVQYVGNNAKSLHLSVEASLKKLRTSYLDLLYVHWWDFDCSVQE VMDALHNIVAQGKVIYLGVSDTPAWIVSEANTYARMAGKTPFVIYQGAWNVMERSFERD IIPMARAHGLALSPWNVLAGGKLRTDSEEKAHADARKKGDGRQFPGAAERNEKEIAMSR ALEKIAREVEAKSIRAVAIAYLLQKTTYVFPVLGGRKPENWQQNIEALDISLSPTQIKE IEDVVPLDPGFPNNFIGDGSDINFFLQLEVNMQRVSLQQPLKPGNGVTTAQN" ORIGIN 1 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 61 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 361 nnnnnnnnnn nnnnnnnnnn nnnnngtttg acagcggagg ccgagcgaac ttacactgaa 421 cgaggacgag aggagttgat ttgtaaatga cttgtcgtag tgaatcttgc cagaacattt 481 tagctgcttc tcaacttgga ttataatgtc ttaataatga catgattatt gtgcacagaa 541 gacttgacat tcgtgaaact gacattaaaa ttacagaact cttgaataca taattcatca 601 accaaaatct aaagttcata accgtcgtcg taaatatatt atacactaca ctcctcattc 661 ccgtcacaaa catggatggc ctatatcacg gcttcgcgag aaaatcccat agggtccaac 721 taaaagacat caagaaaatt aatgttttca caagtttcca agaaagagtt tatatactga 781 cccaattcat aatagccttc ccttaataac tgctgaggct ctgctcgact tccgagttac 841 ccattactat gtcctcggag ggaatatcaa ctggggacac ggaagatact tcggtcaagg 901 gagacataga aggggaagga agcacggaaa atagagcagt gctggagtct tctgactcgg 961 aagtcttgaa cctttttgat ccattagaac taaagtccga ctcaggagac gaagaacgct 1021 tgggccgctt tcccaaagat tttgtcgaag gggtcggtga cagtnnnnnn nnnnnnnnnn 1081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1861 nnnnnnnnnn nngcaggacg atttagtaca gctgatggtg gggtggatga ttgggcagaa 1921 taagggacaa gggcaccggg atactttgag ggtccagcgg tggcagggaa gaccgtggaa 1981 gttttaacac tgggagtagt gatagaacgt gggcctgcag cattagagcc gtcaccatga 2041 cccagaatgg aatttgaagt ggatggtacg ccgagaacag gtgcctttgt cttatttttc 2101 tgcagaagag ctttgttcac aaatcgtcat cgagtgacct ttagagacta tacatacctg 2161 attgaccatc aatataagat atctatcctc tgaaaagcca tatgattcta gggttctgtc 2221 gtcatctttt agtaactccc ctaagcttga tatgagcgat ggttcacaag atacaacaca 2281 ttacttacca gaaaagacaa ttttctgtaa atgagcagaa aaaccttggg attcctcaat 2341 cttgctcttg atgactccaa tcgagtctgt tggctcagca tcaatctaaa aaacagtgag 2401 aaaatggcga ggtgtgcaac aaaggcagaa ctagcctggt aagagtctgc ttggagtgtc 2461 ttgattgtga ctttcattgc gattgaagat tggttctgag aaagctacga tggagagtta 2521 tgttcagaag agggctttgg gatgggggat gaattgacgg cgctggtgcc tcttcttgta 2581 ggcctgtggt agcgagatct aaaaatgatt cattgtcatg ccggaggtat agcttagtcc 2641 agaccgacat cagaattcga gacgtgaaat tgatttcagc gctcactttt tttaacttca 2701 cagtagacgc tgcagaagaa tttcatttga tttgaagtat ttctcgaaac cttgagtact 2761 caattcgacg gatttccaag ttctagctct ttgacgcgtg tctatcgtgg cgctagtgca 2821 agtgttgtaa aacacatgta gatccgtaat tgttgatgtt tatacgtact cctgttgttt 2881 tgcatcgcac tacacatatg ctgttaaaac gtgttcgaaa gcgatgtggg tcagagcccg 2941 atcacgtcga acaggcgttt aaacgtcagt gtcaccctcg gccccaatgc aagtccaagg 3001 cttcactcgc ctgcctatga cgtttgccga accggtgttt tccggcagaa aatggaccgg 3061 taacgtcatc ttaatagagt ttgggaactc cgctcctgcg ttaatttgca tcatgtatca 3121 acgagttctt tccgctctgc gtctctactg catgttcacc acgcatcttc gcgtttatgc 3181 tcaccttttg tcttgcgctc atgtccaaat ccacatctgg ttgctaacgt tcttgtacac 3241 catttttgat tacgcacatc tccatacatc aaaagtgttg gctacaggtt cacacataag 3301 tatcacctca ctgcacacat ctacaacttg caacacgaaa ccgcattctc atttctctca 3361 aaacgcatgc atgcatgcca acagcagttt tctcggaact ctcggcgacg cagcatgctt 3421 ctcttctact tcttcattca accgggctag ggaggaccta tgactacacc ttctttactt 3481 aacacgacaa caggaatggc taacgccgca cttatcctga caatcacata tagaaacggc 3541 tacagctatg ccacgacata gtacatcttc ttttaacccc ggcgcctcct tatcatccct 3601 agcaccacac agggtttgat ggaatcacga ttcagagtat ctgaaccttg tgtcagacga 3661 gtcaatcctt cacgccgata taacccttgt ctgattatgt ctgttccgta tgacaggagc 3721 aggtcatttg tttctagagc ctatttcctt tttagggtga ctttgggaaa tgagcttcca 3781 gggttacctg gcctgagcaa atacatagta agtacatcgc attcacatta tgatgatcac 3841 aatgcccctc tgctgtacat caacttcagt tgattgtcac actatctgtt cataagagac 3901 tacagctgtg gttcatattg gaaattaatt gaattggagg actttgcctt ctatccgctt 3961 atgcttctgt gaaacaagtc cgttcaaaat agtgataggt gattttttcg ccaacatgca 4021 ggcaattatg taagaggcag tacagggtac atcaccactc aaacccgtcc caccttgcca 4081 tctctccttc cgtttatcct ccctcgtctc tatccaccgc ctcaatgagc gtctatactc 4141 catattcccc aaatctttct cgcttcaccg tttctcacgc agaccctacg agccgtgcaa 4201 gcggattcca tacttcggat gcacgttcca acttggaacc caatttttcc tctgataaca 4261 gctgtcagaa ctgctcctct taccgttgta agggtgacga cctcgagttt cttcgagcta 4321 tggacgaagg acgttatgcc tatcgatccc gccttgaatg ggtgtggcat tgtatatgcg 4381 aggctgcacc acaagcttat tggtcagatc ttcaacacgt ctggcacact ctcgtagaat 4441 cagacgatat ttggtcaatt tgggaggatg gtgatgattc gaatgtgcca ttagtaccaa 4501 tcctcgagac gcgttatgtg gacaaactac agtacgacaa ttggcagtct atcgccctca 4561 tcatttcccg aaaagcagat cttcactcaa agaatcgttg ttctccgaaa ctcactccct 4621 tatcttcact ggtaccacaa agtacctcgt ttcatatgcg tcttgccacc atgctctggc 4681 aaacactact ggccactaga cgtgtcaagt accctcgaaa cccgtcctca gtcaactgcg 4741 aaatcccctc tctcattcca aaatggtgga acatgctccc gcaacttgtc aaagacaatc 4801 ttgtcataga cgaccattcc tgggaccgat tccgtacgaa gcagaagtac cgagaacatt 4861 cctgcatgga tagccttcct catgaggaga tgtggtcgac atggatcact gtccagacct 4921 tgattggtgc atctatacct ctagacatcc ctctgaatgg cgaaaattgt catcaatgct 4981 ctacattaca gtatgtaatt aacactatat tactttttgg aataatagtt caaacacatg 5041 cttaggaaaa agccatttgg cagatctgaa tttgtcaaac cccatctact ggcactgtgg 5101 tacattacgc aacgagcatg tcaagggaga gatttcgagg agggccctag ccacgtatgg 5161 gatagccctg gcatactttt gcatttcagt gtcaattata aggccttgga cctcatgaag 5221 agccttctca accaggcaac tcttcacaaa ctggatcaat ggcttactga catttggtca 5281 aattctgatg atgaatttga caactcagat ctcaggaaac tggttggcac aaacctgaat 5341 tccattccct ctccatggaa atttgacttc agtaggaatg agaatgattt agaacctcac 5401 tggacagaaa cacaaactgc aatatccaaa atatctagtt taaaatcaag tgttgatcct 5461 gattctgatt cagtagagcc agcttcttgg gtttctgctg tggtcttgtt tacactagcc 5521 aggatttatg gcttaggacc acccactgct taccattttg tggaacacat caaggaaggt 5581 aatctggatg accttcttaa aaaagcacca ctgttatcca acacaccagc tttcaagaaa 5641 tttgatgaag ctctagagag atctgatcac acatgctggc cagaaaattc ctgtggtcca 5701 aactcatata caaatttgta tttttctggt tactcattat tgttggatac tcctcgtgtg 5761 ccttttgttg gatgttggga gtgtactggc actaaatgta ctgcatgcaa taacaaaggt 5821 gacatgtatg atctttcttt tgtgttggat gaggaccttt tggttcctct gcaatccctg 5881 tcagacacag gaaagaaagg aagagtaaaa agattaatct acaagctcgt gagttagtct 5941 gtaaatattc caatgtgaca ttgctaatag gtagtgattt cagagctttt accgggaaga 6001 gtttaattcc tcttcctcac catataagca taatgacttg gaggtgctca gcaaaaaact 6061 gagttctctt tctgtaagta tcagtgttca ggccaggatc aagacgtact tcacagtaac 6121 tcatcattaa tcctttcttc ttcacagacc cttttccaat atgcacttga aaatggcaaa 6181 gatatgaagc tttttgatcc taatggcgaa atattgagat atggtcattc ttatgatggc 6241 tactctgact ctggtcctga agaggtcttg caaggcttta accatttaac aatccaaatt 6301 gccaaggtat gttgtaattg atcgaaacca tcagtcctct tattgaaccc agttcagcct 6361 cctcaactga cctcttattc tgaaatggaa acccaaaatc ttgatctctc agcaatctca 6421 gcacccaatg taagttgtga tccatcatga gttgcaagat cagccagtta atttgctata 6481 tactcataca gaactcagtt cggcttcatc agccagtttt gcccaacaca tcttatgaat 6541 atcaacaaca catgtcaggt tcacatgaac agtctcaaac ccaaaatact gtaagtaact 6601 gatctttttt tctaggattt tgatttcaga ttaagatgta atttatgtag gcttacacag 6661 tggatcagac agtcaatcat gcgtcttttt ctctgccatt ctatgataaa ttcttgggtc 6721 ctggacctcc tcctgtttca tctgtgccca tcccttctgg acctcaactc tatcctctgc 6781 aagaccagtc atcatcattg agtgataatc ataatgtgtc tctccaaaat ccagaactat 6841 ctagcagaag agctctggaa ggttcaatgc atctcataca aaaccatcct attcctgatg 6901 aattaaacct acaccagctc gaaaacacaa attcattcca acagccactt gtcaatctac 6961 aatccggagg tacacacacg agtgctttcg tgctggaaac cggtcaatgt aatacttcaa 7021 agtatgctca atactaaatt attgtccgag taccaaattg atttttttaa tcagagctcc 7081 aagtgaacta cgggtagatg agatgcgtgt aaaaattaaa gagcaatttt tgtctatgct 7141 gagtcggtct tctattcatt ataacacagt gtttccctca ctgactcgtc tatcaacaaa 7201 ctcctacaga atcccacaac atcgacacag gggataagct tccttggcga aacctgctta 7261 aaattctcca agaacgtaaa tgccaattcg aaaactggcc tgagggtatt cctcatccac 7321 atactcagaa tggaattgaa aaggcacccc agaaagagat caaggcatta tataaagcat 7381 tgttggataa ggaacgtccg ttgaggatct gtagaattga cagaggctct ggaggtgcag 7441 atctaaggtt tatcttacag gatcctccag gatctgggag taatgccaag cgaaataggg 7501 atgaacaagg aggtgagatc gaagaaaggg aaagtaatcg aaggagaatg gactagtatt 7561 tggatccgtg atgatgtcct ctcggaattg ttggaggtag aactctcgta ccaattattg 7621 ctgtttggaa tctttaaatt gtaccatgta tgcaacacag attcgttgaa ttatttatta 7681 actttctacc tcctcgactc tgcgtttgcg gtgagtctag cacccaaagc ggtcggtatt 7741 atgatccgcc ttcgcaatga caaagttgca atggcaatat gatgtatgtc taagtatcag 7801 ttcatcttcc gcttcaaata ttccccattg atgctttggt atcttgtttt atacatacga 7861 ctggagactc ttcgaaccaa agaactgtcg aattcaatta tatcccctct tcaagcgtcc 7921 atttcaaggt ccaccgtcag atggccaaat tccaatgctc gacgccacgc gctttgagct 7981 taacaactct caacttagca gtcgacgcta aatttacggt tgactctaga tcagtggcta 8041 aagctcgacg cggttcttac tatttcaacc cggttccgac agtttttcct tccaatcttc 8101 tttggaaata ggtccacaaa aagacatatg ggtcaatctc aaatcctcgt gaacaacacg 8161 atgtgcattg cgtgttcata tacagagaag agaacgagca gaaatatatc tttacagcgc 8221 taggcttacg gtgtgaattg gagcattgca taccctggat tgacatcttt gcatcgggtg 8281 atgagcttcc aatttccgat gtctgggaac cttatcaact ctcaggctca agatatgagt 8341 gcaggcagaa tggcacgcct gaagcaacgg ttgtactcaa tagcaataca tccgtaactg 8401 tcactgtgaa agagaagaca ttttttggat atagtttgta tcatcacaga gtaaagaaaa 8461 agttccccga atattatatg gcggcgcgct tatcctcaaa agatctcaag tcacacatga 8521 cttagcactc aggactttct caaaagttcc acttttccaa aaacgccgaa aaaaaaaatc 8581 tagggccata ctttttggct aggttctgtt tactattttt agatgtcggc cgctttttta 8641 taccttccaa ctctgatagc acccgatata tagaataatt aatcatacgt tcgctactta 8701 gacctagtag ctggtttttt tttttcctgt aaggccgtga gcgggttaga gatatgtaaa 8761 aactcgtatt gattgtaata gcttataagt aatagctttt agtaaggtcc taaccaagtt 8821 ttaccgagtt ctatcaagct ctgaccaagt cctaaccaag ctctataagt tccaacagag 8881 tctcctctgt tgtaaccttg agaaccaggt tagggtgtaa tgcaatatgc ttttcgctcg 8941 gtcagtcccg atatggtctt gtttgtcaag acctttatta ccaatcgact tgtcactaat 9001 gtggtcctgt ttggatcaga aacctctgac ttttgtactt gcgatggccc acttgacttc 9061 atagatttga tttttcgaac agtgtgttag ggtgggagta cgtctcgaca gggtgggagg 9121 tcacggtaca gatagcagac gagttctttg gtaagcctcc ggcctcgtaa tgtttttggc 9181 taatgacttc gtggggttat caggtggaat cattatggat gtcaatcaag gagaatgtac 9241 cgggcgtcca cagtgggaac atcgcttggc ttcagttgac cgaaacagac ctagccgcgg 9301 agtcatggtc ctgctacacg aacgcgcgta atgtgacatc ttcgaatccc agcctccgag 9361 aaattgacag gaagttggac ctgggagtca gcaggctcaa gctgaccagg gaaagatcaa 9421 tgccgcacaa tatcatctca ctcttcctcc aaacatcact caatgggttt cccttggagg 9481 ctactgcgcg ccggtatact tgccagctcc tacgtgtcga tacaagcact agccttgccg 9541 gaatccttat ccatctcttc gagtccgtcg tcgatatcgt ctgcaagtac ttattgtaga 9601 ttccaaaccg agggttatac gtacaacttc tgtccgttgc tgcaacgaag cgctttcaga 9661 gttctcccta cgcgagaaac tgctcttggc aatgacaatg gatcatacac gttcagaact 9721 ggttctgcag atgacaactt gtatctgggt tcggtacgtc ctcatccaat cttctactac 9781 tagaccattc tgattccctc ccctcttttt ctacgaaact cccagtgtcc agtagacgcc 9841 ttcgtttgtt gggatggtga actttgtatt ccacttgcta actcatactc tttctcactc 9901 tggacctacc agatccaaac acgtcgtcct ccgtcgtcgt cgccgaatcc gtcgctctca 9961 acggtatctc acacctgaac tacgttccca atgatagtca gtttgacgtc tttttctctt 10021 gacaatttgt gcgcactgac atacggtatt gacaacccct gcagtggtct cgtccagttc 10081 caaacctctc gtgtttgtat tcaacggtac aattcttgac gccaaactcc aatcagtgca 10141 tatcaagttt atttgtgacg agagcgtcga tggctttcaa gtgcgtatga aacccttttc 10201 tctagtacaa gtctttactc atttctttct tgttaaggct tcagtatcca gtctagcttt 10261 tttcactggt ttttatgatg gtgtacattc tttcgaatgg cgatctagtc acgcatgtcc 10321 cagggaactt ggtcaattcg tcgacatgga tgatcagcaa ctcgaaaacc ctgatgaaac 10381 cggagacaag agtctagcgg actctatatc acgctacaaa attgcgataa ttgtagtcgt 10441 cattgggcaa gtctcatagc tactgtgccg ctgcaaagtc aatgaactga cgaacggcaa 10501 agcatcatac taatcattgt gatagcctat ctaatccacc gtcctccaac gaccctctta 10561 gctacttatg ctcgatggaa taggctgatg cgagaatacg ctggtttggc atggagatct 10621 aatctgagct attagatgca aatacccgga gggtagttta aagaatgaga tgggcgcagc 10681 ttctttaaca ataggttgac atccttatca ttcacctcga gggagaaact tatgacgagt 10741 atggcatttt taacgatagt taccaagtga cacccttatc attcacctca agtttattca 10801 tttcaccatc gatttgacaa aaaaactatc ttcaagtgcg caatcgtaat acgatggtta 10861 tcggacattt tccctcttct acatcgccgg gaactctaac ctgccagtcg accaatgtaa 10921 taaccccttc tccgacaaca ttgggaacat attcactgaa tcttcaggta ttattatcga 10981 cgtttcacat ctccgatcaa tcacctgaac tcctacccat cgtagagttg gtaaagcagc 11041 tagagctgta tctaatctcc accatggtac tctgaatggg ttaaatacga gggaagtggt 11101 ggaaaagctg aacccaaagg cgaggtgagt tatttctgtg gtattggtgt tggagatctc 11161 gaaaaattga gcgagtccgg atattagatt ttgagtggtg ttgtcttgaa gaccggagag 11221 gactgcagtt agaccgagtc gacgtaagga aggtaatcgg tcgagatgga ttatacctaa 11281 agatctaatc attaatgaca gacagacaga cactacttcg tgagaacgaa gctattcgga 11341 acgtaccagc tgggggtcca cgtgtggaca ccatgtcgaa ccataactcc tccaacttgg 11401 tctggacaga ctcgtgatat aataaaggac cccatggcag ctcaggctca gacgatggct 11461 gtttgagcgc gcaacggaaa actgccagtt tatcaagtcg tgcaaggttg agaggaggtc 11521 gaatagctga catccatcca aagaacaatt tgttgtcttc gatccattcg agtttacatg 11581 ccgtgacgaa gagctgcggt aggctcgtat tcctattctc gtcgtcgtcc tcgaaagggg 11641 ttattatgct cggacgagtc agttccaagg taagattgga ataacctgtg ccttgtagcc 11701 tcaagtgtat caaagaaggg gagataacga ttgtcgtatt tagcaggtcc gtcaagtcgg 11761 tgaaatggag ggatagagag atcaacgagg aacgttgaat gacgagccta atagcgtctt 11821 gtaatggctg tggtagttcg ttccaacgag tcgggtgtga ggagaaagac gaggctctcc 11881 atgtgaaaca gaccagattc gaaagagatc ggaggataaa gaggagatca aggtcgattg 11941 gtgtccagtt ggtaccagaa tcgaggatag ataaggatct gacatttgag atgagatgag 12001 gggatgactg gagtagcttt ctggtcgcat tggtcgtatg ctgatatttc acggattttc 12061 cttctgtttt ggaacaagta atggtgagat gcgagaggag gtgccgttgg caaagacgga 12121 caagggagga atggacgagg gataaaaatt tcacggcagc tttgtccttt ctagcaagga 12181 gctcacgaat gattacttca ataatttcga ctggcagaga aagcatcgcg ccctatggac 12241 ttgggtggga gtggggatat gtggatgggt ctcgtaatag gtctcgtata gctgaacgag 12301 tgcacactgc ggagactgaa tcgagagttc tcaccggttt gcgggcccgt agcagagcgg 12361 agttggacct cgatcattgt ttggcttcca gactaacact aacacttcca tgttaggata 12421 ctttctcgaa gcaagtgcaa ccattcctct tgtcaatacg tgacaaggag aatgaatccg 12481 atggaagcag gtgtgtcttt tctatcgacc ctagatgaga tatgttcctc cgatttctga 12541 taccccacat tatcgctgtc agaacggtca agtctttttc tcatcaatag gaacatgacc 12601 gggattccac tcagtttctc taatcggtct cttttcttgg gattgcagca gtgatatacg 12661 gttgcgcaga tccttggtct agttgatttg tccttttttt actgtcatta ctatgtcaca 12721 gaaggcccaa tgatactcgc gataagatgg tactgcactt gagcctccct ttgcaaccca 12781 gccagtgata gcaggtatgt cagtcccata gtgggcccat atctgcctgt cgatagggac 12841 gaaacttcag cgattacgta tcggaccaag ctacatggtt ctgttactgt acccgatcct 12901 tatagtggac tggaagctcc ccttgatgaa agcgcgaaaa ctaaagttcg tgaaaaaccc 12961 ttagtgctgc tgcttttttg attctcagta gggaatggta cataggcctt tgttcttgcc 13021 caacgcaaat ttgggcgaat ttatctagac gggaatcctg acaagtgaga gtcatcgttt 13081 gcgtttttct ggccttacat agactcacag ctgatggtta ttcgctagag aagtatggct 13141 tgagacattg aaacagagtt ggaactacaa acgattcact gtcccgagac acgaaagcga 13201 tgaccatata tacttcgaat acaacgatgg tcttcagtct cagttgtccc ttcatcgcgt 13261 gaaggtgggc gatgaagata ccatccttac cgagtctgga ccaggaggag aactcttttt 13321 tgatcccaac atgatctcgt tggacggtaa cgcttcactc actggcttca tcatgagtcc 13381 ttgcggaaag tattgggctt atggcgtgtc tgaacatgtt cgttttttgt cttgtcacgt 13441 ctctgtaccc aacttcactg acgcaacact gggatagggt tctgattgga tgacgatata 13501 cgttcgagaa acttcctctc cacatgtacc gtcacaagaa agaggcaaag atcctggaag 13561 aatggatgac gaggttcgac actctcgttt cttcatcgtg tcctggaccg gtgatagcaa 13621 aggtgcgcat ccacaggcga ctggctcgga tcgcgtaaca gactgacggg cttattgtag 13681 gctttttcta ttctaaatac cctcctgagg aaaatgaggg taaaggcaat gcaccggcga 13741 agaattgcat agtcagatcc ctcagctact gtgcaagcct atttgttaac atttcatcag 13801 gtctattatc atcgactcgg tgagaaacag gagaatgaca cccttgtcca gtgagtatat 13861 ctatcgtttg ataatgtttt caagctcaaa aagttttcag taaggattct gggcatccgt 13921 tttggctttg gtccctacag accaccccca ggttagtact gatttcaact tgcgtatacg 13981 tttgcacgtc cttgtattga ctcaacgtgc attagtggca gatatgctct cctcgctgcc 14041 agtgtacgtc tattgactct ttttcatgtc tatttttctc tgatcatgaa ctagcgtgat 14101 gccagccaca ctcagctagc taagatcgct gatattcatg acaacgatat cggagccagc 14161 atgaaatgga taaatcttca cgactcatgg gaggctaggt ttagcatgtt cgtaataaat 14221 gtgttccttc aaactttact tcaactgata actcttctgc gacaatgcac agaatcggag 14281 acgacgattc gaagatctac tttatgacaa acctccaagc tccgaattac aaagtagcga 14341 tatttgatgc ttgccatccg agtccagatg cggacctcac gacccttgta gccgaagatc 14401 ccaatgcact tcttatagcg gctagcattc acgccaagga caaactcgcg ctcgtttacc 14461 ttcgagatgc caggcatgaa attcacgttc atgatcttgt cacaggacga ttgcttcggc 14521 gtattcttgg ggatcttgtt ggacaattta tggtaacggg gcgacgtgca gacaatgata 14581 tgttcatctt ttatagtggt ttcacctctc ccggtacagt atatcggtaa gttttgttct 14641 gtagtgatca cacacaccag ctccgctaat aaacaacgtt tgtaggtaca agtttgacga 14701 cgaaagagat acgtgctcgc tgttccgtgc catacgaatc cccggtcttg acctagataa 14761 gtttgtgact gaatcggtaa ggggcacatt accttttaac tcttcatgtc ctgatattcc 14821 taattacgtt taggtatttt atccatccaa agacgggact tcgtaaataa ttcgttggag 14881 cctctaaaaa cctgggctga caacccgtat aggatccata tgttcattac ccgcccaaaa 14941 gacgtgttac tcgatggaac ggcacccgtc ttacaatatg gttacggcgg tttcgcacta 15001 gcaatgctcc cgacattctc cgtctctacg ctactgtttt gcaagattta tcgagcgatg 15061 tatgtggtgc ctaatatacg gtaattgttc ctatagattt ttttggctct gtatatgtgc 15121 taagcaatca ttaagtgggg gatcagagta cggtgaatca tggcaccgag cagtaagtca 15181 cttgtttaat tgttacgagc tcacgattga ctcaacatta tatagggcat gttgggcaat 15241 aagcaaaacg tatttgacga ccttaacgca gctactgaat ggcttgttgc aaataagtat 15301 gcaaacaagg atcgcgttgc tatacgtgga ggctcaaacg gaggtgagaa gcctctctgc 15361 tctactaaat agatgaaacc gggatttgaa tatgcttttt ttacaggtgt tctgacaact 15421 gcgtgtgcaa atcaagcacc tggactctat cgttgtgtaa tcaccattgg aggtataatt 15481 gacatgctca gagtttgttg acgatccagt aaaaaactct cttgaaatcc tcgctgatgt 15541 cgagtctttc agtttcctaa atttacgttt ggcgcgcttt ggtgctcaga gtacggcgac 15601 gtatgtgtct tcgaaataac tggatatttg gacatgtctg acttacagag atagcctgaa 15661 gatcctgagg ctttcgattt tatctacaag ttaactaacc taatccctct gaactcgtct 15721 agtcgctcaa agtcttctca ggtactcgcc ctatcataat attccttcgg gagagacagt 15781 catgcccgcc atgttattct ttactgctgc atacgatgac cgcgtttcgc ctttacacag 15841 taagtgctca aaatatcaag atctgtacct ttttgatctc cttgcactaa caatcgtttc 15901 ctggcagcat tcaagcatgt cgctgcttta caacacagct ttccccatgg tccaaatccg 15961 atcctgatgc gcgtcgacat gaattcaggg cattacgctg gcaaggtttg tatttgaaag 16021 gtctcatcta aagcttgtct ctggcttaga ctagactaat ttttgtagag tacacagaaa 16081 atgctggagg aaacggctga cgagtacagg tgggttcccg accatggctc ttgagataga 16141 cgttaattgg ttgactttat ttgtctagct ttattgggaa atccatgggc ctcactatgc 16201 aagttgagaa caaatcagac tccaaccgtt ggtcttgtgt agtgaattga tgatccctcg 16261 tgactactca ccgaatggtt ggcgcgattc cgaatacaca ctgtggaact gtacccaaac 16321 ggtgtttatg tttttcttta tcctgtgaag attttctgta caagtatgtt cgagtctaca 16381 atgcaaattc ttgaaagaat tggatcatat cagtaaattg agtcatattt cactgccttg 16441 cattttctga tagccatgga ccattcaata acaccgatat catgaatgag tttttcccta 16501 tgcttcttcc atggtgaatg tcaaagccca aggattccaa ctgtctgagg cggctctcga 16561 aataatctga tcatataaat caagtgcctt gcatcctcta acgctctaga tcattcgata 16621 acgccgattt cacggataaa cttctcccta aggatttcgc taaggatttg cttcttccat 16681 gctgagtgtc aaaccccaaa ggattccaac tgtctgaaac ggctttcaat ctcttgatga 16741 tctctctcta aaactcagcc cggcgaattg cggtgtctct atcagctgca catgtcaatc 16801 tggactttgc tattttgaac gaatggacat atttgcagcg ggagcaatgc ttcggtatca 16861 ttgatagcgt tactagtaaa ctacctgatt acgagccatg cgcttatact ttatcaaaat 16921 cctttcgccc ttaggacgcg cctgggttta cgagatcaat caattttccg ttagggtcta 16981 tgctttcgaa aaaagccatc gtactcaccc cgtttacctt gttataatcg gggataggaa 17041 ccgtggagga gtgagttttg cgccttgtgg tgatggcatc gtattcatag ttcatcacga 17101 atagcgagac gattgtcttg atcgccaatt ttgcgatttt cactccggca catcggtgtc 17161 tacctaaaac tcgaattaat ccggttaatc aaactagaaa agaaaaagat ttgatatgat 17221 tccaagatgt caacaactta ccagcgcccc atccaagaaa ctcgtacgaa ttcttttggt 17281 gtccaggcga actcaggtta gtatgtcgtt gaggatcaaa tctccaagga tctgtataga 17341 cctcgggatt cagatgtgca tccgcatggt tgtaaactac gaatgcgcct cttggtaatg 17401 atactacgtg atcgtctttt ccgccgggaa tctgcaacgc ttcgcctacg ttacgtcgaa 17461 gcacggtttg gttcataatc aaacgaagag tctcggagat gacgaggtcg agagtaggca 17521 ttgattcttc ccaagctttg attgggactt gggaaagtct gatgtagaga ggctcggaag 17581 tgtcaatgga caggtgagag agcatacttt tgatttcgga acgaagcgaa gttttccatt 17641 gagggtgaag ggaggtatag atgagtatcc aggaagctgc acgaaattgg ttgttacatt 17701 tagataacat gtccatgttg aatagattca ttttactcac tagcttttgt tatattgaag 17761 acgcctccaa atagaaagcc tagaatgaac tgaataattc cctgggtatc catcccgtgg 17821 gccaacagca gatcgatcgg ttcggaggag acaccactag atcctttccg agtctcgatg 17881 tgctccgaca aggctgagaa gaggaccatt acagagtttt ccttgtcgcg ctgagctgaa 17941 cgataaagcc atggaaagaa aatcatccct ggagtgttgt tctttagttg agtgaaaaaa 18001 tgattttgga aacgagataa aaaagcgtgg tccgacacga attcatggct ggtaatcata 18061 tgtaaagtga ccaggaatgt gatctgcgtg agtgagtatc tcgtctagtc attgcaggga 18121 ggaggtgaga acatacatcg ttgatatggt caaagggatc catagtcccc tcttcccccc 18181 aggctgccgt gatacgctgt aggtcaccga gcatggtcgc aatgactgat gtttaattgt 18241 aatgaaaaga gtgagcattg ggcaaagatg ggtgattgtt gtactcactc tcggtgtatc 18301 tattcttccc caacaggatt ccgagctgct ttttgaagtg aatactatgc tcctcttccg 18361 cgaaaagaag ttgcgtcgcg gacagctcgg gtgtctatag gcaaggattt ttttcaggaa 18421 acaatcaaat aactgtcttg tcggttcact tacaggtact gctttactga acattctata 18481 tccctcactg ctactcaagc tcttctcttc aaaaaacatc tttcgtgctt cctgacctct 18541 cactccaata acaaaattct atcattgaat agttaaccat gcagtcaacg gcaatagggt 18601 atatacgcac tttgaacaga tggaagtgga acgtgttttc tccagttctg aagctggatg 18661 tcataaagtc gtgaccatag gcaacggcaa ggacatcgat gtagaattcc ttgaatttgc 18721 ggctcgccaa gaccgcaact tgaagaaggg cgattccgat gaacgtagcg atgatcactc 18781 ccatttttcc caaaaaaagt tcagtaagtc ctggagggta gatgattaga atagatgctc 18841 aataccttcc catcaatgac gccaaagacc taagactagt ggggtggttt cacctgccat 18901 tgagcggagt atgactgtga gaattccatc accgtgggac ttggtttcct cgacccttcc 18961 tcaacgttcc atctccgctt ctattagtac cttgacatgc gctaatccgc ttgtgtagga 19021 tgacaggtaa ctctatacgg tcttttgagc tccgagctgc ggggccccaa gactaacaag 19081 gcacaaaagc tggatgggag aggtgcgagg agtcatcgga tcatctttcc agaatgtgag 19141 tcgtcgagca tccattctcg ctgctcaagc actcacatgt actcacagcc caccgatttt 19201 cagctctagg acgaacaagt catgaaccgt ctttttgctc ttgctgcctt gtcgaaatcc 19261 ttttctacat ttggtatggt tgtccggcct tcaccttacc gatggttgtt cctcctccca 19321 gtcatagcta tcaatggcta ctgttacttc agcacttttt ctgaggattc aatacgtgta 19381 aacattctca tagagactct gatggcctcg gactacattc tccttacgga cattcagcgt 19441 gaattccgac agattggaca gcaagagcca atctataatt tggggatttg ggctcgtttc 19501 aaatggacag tgcagctgtt gttttcacct agaggagtag gatggactca tgaaatgaaa 19561 tccattattc cttcccatcc gaacttgact cgactcgaat tcctccgatc ccggtttatc 19621 tccctgataa tggcgttgat tggcaatgat atagcgttca tcctcacctc cattgaccct 19681 ggattttcgg aacatgcgcc gccatttgat gaacagcccg tcgtatggcg tttctgggcg 19741 actggtctct tctttttcag attaaaatcc gccatcaatg tttatcttct cctcgtggct 19801 ctgcttcttg ttggtaccgg gctgtcagaa cctgatgtgt ggcctgactt cttcgggaaa 19861 ttgtcagatg cttatacggt ccgtcggtgg tgggggtatg atgaattctt acttttttca 19921 gacctaggtt tctgatggac ttctttcaga cgagtatggc atcagcaact acggagggtt 19981 tgtccaacgt cagggacgag taaaaaagat ttcctttctg attcgtcttt ggttttttat 20041 agatcttttc ttcgcacgga aaattcctat ctcaacgcgt ctgtggcttc cgcaccggaa 20101 ccttggcgtc ttcatacact cgactctatc ttgccttttt cctttcggga ctcattcaca 20161 ttacttcttt agacccacga ccgattcggt ttttcttgtc acaggcggtt gtgattactt 20221 ttgaagacag tgttatagcc gcagcaaaca gagttggttt caaaagatca caggctatta 20281 ttcgtgtctt gggatatttt tgggtttatt ttgttttgag ttttactttt ggaccttggc 20341 ttgactctat gaatgctact ggcgtgggag ggtatgatgg gactttggtt ctaggtcgtt 20401 atcgagatag ttggtggtta aaagggttac taactcagct ggatagaaga tagctaacat 20461 agctcatgca tttttgcgtt gatatatttc acttttgttc gtttatatca cttgcttttg 20521 caagctggag atcaaagttt cagaaagtgt aatgtattga tccattttaa ttctcgtagt 20581 tatttcttta caacatcggt cacagaatac ctaaaagtgt tactggctcg tacgacaata 20641 ctactagtac aaaaattgct gattcctttc tcatgtaagt atttcctttc ttaatcagag 20701 catctgaagt gacaaacgat atacatagac gatcaagcac tgctcacaac cgatccgatg 20761 accccaacga tacccgtgac gatgacccat gggaaaccgt tcatggatgc ctcttcgacg 20821 gactggctag cggcttccaa gagagaggac ggcatgttct tcatggcgca ccgaatagcc 20881 catgaatctc ctagctccaa agctgctctc tcttgaggcg tcaagtcagg aacagactga 20941 gcgaaggctc gatgatcagc cttatactcg gcgagcgcct tgggatccaa agctagtttg 21001 gtcatgacgt cagtcatagc tttggaagtg gccagaggct gatactcttc ggggggagcg 21061 tgagcttcca atctagtgat agcagcctgt tcgttttgtc catagggagg tagagtaggc 21121 acgtcgggtt cccattgatt aggtgggtag atttgggtgt gtttgtcggg aactttacca 21181 gcaggtagga attccaagag tcggatgata tcggtgttga tatcctttct ggcctttgga 21241 gggatgtaaa aagtcgaaac accacctact cgtttggcga tttcgggttc acggagttgt 21301 ccgatcgtga acttgtcggt gacgggatct tggtgaggca tcatagctgc gatataatgc 21361 acgacggtat ggtctgggcc gtattcttgc tcgagacggt caaccagaat ggtaaatttc 21421 gaattctaaa agaaaagtta aacgtgttag acacaaatcg atcgaccatt acaggatgga 21481 aaaatcctta cgtcgaatcc gctgaaattg aagtctgcga taccgacgca tccaacttgg 21541 aaaagaatga ggtgactgtg aacgttcact ggtctctctc tgatgaggaa atcggatgct 21601 tcgtaggtca agcagccggg gttcgagggg tcgatgcata agtcggcaaa gaggcagtcc 21661 tctgcagata ctcctggaag catacgagct tggtatccct cgcttctggc gatagccaat 21721 gccctgtgag aagggttcac gaacacgccc ggatggccat agaatacccc gacaacgtcg 21781 aggccattgc ggacttcctt gagcatgagc tatgaagaat tgtcagcaca agaccttagg 21841 aaggatacga cacaaagtta ttttgatccc tacctcagcc atttgggtgt aagtatccat 21901 tctagacttg ccattgtcgt agtactgata caagtcgaca caattcttgt tcttggtgag 21961 gataaaagcc tctgtcgcag ggtcgatgac acaatagaag actttggaag cagcttcaat 22021 gtacgataag gcttggagcg tcatttgacc gatgctctcg atgcctgtac cgacgacgat 22081 gagcgaaccg ggtttggttt gagtagaaga ttccatggtt gcaagaacga tttcttgatg 22141 agagacgttc caagccctgt gagcccttta taccccactg agcccatcct ctggcgctcc 22201 cttaaagcca gtaatcatat gcgttattga tcactttagg tggtaacgga agtctcttct 22261 attttcagag gcaactatcc tgtctcagag ctaaccagta ttctaatatg attttctgga 22321 acacctcgag cccaattagt cttttccagg aatttggagc aatgaatgac ttgttccata 22381 tgcaattttc aggtcagctg tgggtgcaca caagaaaggt ggaatatacg agggattgcc 22441 gatgctggct ctatctttgt ctttgtcctt gtgtttctct cccatcattt gatagcgatg 22501 aattgtctga gtcgaaagtt tcattttcgg gtttctagag ccattcacgc tgtcagagaa 22561 taattccttg atcttcccct tgtcgacgat gagatctata ggatttcagg tgggaaacac 22621 ttggacaata atccacaagg gaaaacgaca tttttttaca caacgaaagc ggtataaccc 22681 tgcgggggtc accttcatgc tgcccacttt ttgatacgcg agctctgccg cagtgccgct 22741 catgtagtgt aatgacgtac aatttatgtt ggtgaatttt cactgactcg cgttctatca 22801 tggctgacag tgacaacaag gacgacggtt tttacaggac gattaaatct cgtttatgta 22861 ccttaccaga gtccggattc tccaaagttg aaagaatctg gcacaacgtc aatcaacagc 22921 aacttcgttt tatttctcag gctcggccag gaatcggcaa gctctcgcgt atcataaagt 22981 ggggcatgaa ggtgatcccc gccctggggt tccagtctag gcagcgtggc tcaacttaag 23041 tagtctcgag cccgagaggt gcacttcaag gacttgagag ggtttgagta cttcagtttg 23101 atgaatattc ttgatgctac tagtagtgcc agtttgagtt caggaattaa aaatcgcggt 23161 ttaagcaaat tcatggagtt gttgatcaga atcatctttt tctaggtcga acgctgagca 23221 aagaaaattg agacccagac ttattgtgca ttttttggta ggtggttgaa taaatcattg 23281 taacgctggt gcagcgcagg ctggtggcta ctatttcatc atcggaaaga ccttcgtcct 23341 gcaatagtca attacaactt ttgatgtctc ctggactcat aagacactaa gtatgtcaaa 23401 tcactgtgaa gctttcaata gccaacacgt tcttttctcc ccttaataat ctacagcttc 23461 aacaatcagc cacgaaaata atgaaccgat tggtccaaga tttctgacct ggatttcaaa 23521 tgcaaggatt tcaagtaatc gggtaataag gatttaccgc ttcatggaga tgtaatcaat 23581 tcaagctctg tatacttggt cggtaccagt taatgagttt tacgatgaaa aatgttcatt 23641 tcgagctacc gctctgagcg tggtgtctca atatgaaatt tatgatattc aattgcgacg 23701 acgttcgtat ctactagata attcaactca gcaaggacta gagggttatc ttgacagtgt 23761 gaacggttct agaacttagg aaagcctccg agagtggacc tttcttcaac ttgatctggg 23821 agtcgggttt atagggtaga aaagaacgat tacgaattcg aactccggaa aggagatttc 23881 cttcgttgaa cggtggagat acctgaatga caggacaaag aaggatcttt ccttgaacca 23941 gtaaatttct tgtgatcact tgctacggaa tacctctaat ccgtcggata tttatctccg 24001 gtttacgttc tacatctcag cgagctgagc taaagcagaa tcagtaccac accatttctt 24061 ttgtttaaga ggggaaatat cactgacaga tcactggtac caaatgtcga gccacccttt 24121 gagctatcat ctcgtttctc cttatatcaa agccgacttc aattccacga tcatctctaa 24181 ggagacagtg accacttggg tccaatactc tttgggatgg ttgcagttgt cagttgcgtt 24241 catcctcgtc gccactgttg ctgtctttgt caagaataaa gtgcaacaaa tctggattac 24301 ttgcctgttc ttctctcgcg cgtacgactt gatcacgtct aaacttcgag ttagcagcag 24361 taatgcgttt tcctttctcg tttttgacgt aagagtccaa atatctccag aattatatca 24421 cgatgacact tgtacctgta gcttcctatc actgcggtca aaggcaaagc agcacgcaag 24481 tctttctttg aagatagaaa tttgagtaac gctgaaggat acaggatttt cgggggtccg 24541 aatgctgtag gttttagatc ttcatgaggc aataacgtcg actcagcttt gcgttagata 24601 tccaaagtgg acgagaacca tgttcatcct gacaaagacg agcatctcac tcgttttatg 24661 ttgcgaatca cagatctcgt acagagggac agatacacgg atggtaaatc gttcatctct 24721 agatgttctg acctttatta aatctgatca aatgtgcagc aatgcctgcg ttgttcgacg 24781 ctgttggaga cttgatggct acttggggga accagggtat aatggatccc ttccagaaca 24841 tctacgatgt tagtctttat tacccttcaa taccacctcc taaataactt tgggctttgt 24901 agatcacgtt ccagattaac gttcacatgg ccacttgtcg cgaattttcc tccgaccttg 24961 ctacgctctc cgagttcaaa gctcacttct tgaacgttga aaccaacact catcccaaca 25021 gtgcggtatt tccttggtta tatcatagcg ttaggcgttc gaaggaagca tcagtcaagg 25081 ctcttcactc cacgctagcc cactttgttg aaaaaagacg acaggccaca gtgccgaact 25141 cggatgcgat cgatattctg ttggctcaaa atgccagcac accggacatc gtcttacttt 25201 cacttggatc tatcttcgct ggggtttcta acacgagtaa aactggtatg taaattcacc 25261 attctcttta taacgtgtcc tgacttgaat aaagcaatct agttccttat cttcattttc 25321 attcatcccg aatggaaaac cgctattctt gccgaactga agccactggt cagtcagtat 25381 ggtaatgccg ctgatcccgt gcataggcaa cccgctatga tccctagttc tgtttgggac 25441 agttcaatgc cgaccattga ccttgtcatg cgtgagacca tccgtctggt tatcaatcat 25501 accgctctgc gtcgcaacgt cggggagagc tttgatatgc ctgggggtgt aggggagatc 25561 aaacgggggt cgttcttggc atatagtctt gcagacgcgc acttggaccc aggagtgtac 25621 tccaggcctc atttgtttga tccggagagg ttcagacctg acagagaaga agacccttct 25681 gcattcctgg gatttggagc aggtacgagc tcgaaatggc tctctttctc gactgtttct 25741 taaactttgg cttgcttagg tcgacaccga tgcttggcca gtaaacttgc cagattggaa 25801 atcaagtcta ttgtagcctt gtttttgatg acatacgact atgaagtggt cgatgcgaat 25861 gggaacttcc ttcaaacgat ccctgctcct gattacaatg atgttcaatt ggtgggtttt 25921 aagatcaggt atttcttttc agtcactaac ttgggaagtg gctgttgttt gttaggcaag 25981 acctaaggat atggaatgtt tcctgcggtt caagcggatg gaaaatcaca actaacataa 26041 atcgccttta agactttcaa tgcttcttct agtatttcat tgatgtacag atttgagcat 26101 tgttgccagt aagtataaat tctcttcaag tttctatgtg cttttagtat gtgcctttcg 26161 ttgtagttgt tctttaactt gtcaaaaaaa gtgatttcgt gttcgtatct ttagatttag 26221 tgggaaaata tcggccccag aaaatgtatg caatgcgatc gtactttgga taagcatata 26281 tctagagcct cgacaactga cagagtcagc tctttgaatg ccatattatc atgtgcaagc 26341 tattcctacc ctgaggaaat gtttctacac agtaacacac agaatattca gaacattcca 26401 gtatctgact cagggctatg gtcgacatga ttgtcaggct attactctat acccgatttc 26461 agatttatgt agtaagcaac aagaataatg gtacgaggcc ggagtttcag aagactcatc 26521 cttactaaac ctaaacttca actcacacat atctccattt ggttgatctt gacattcgcc 26581 ggcctcgtat ctgcagcgct ggacctttca taagaggttt gaatagacga actcaacaac 26641 caccatcgat atcaacgcta ttcactcctt cctgcagacc atgaattacc ttttcgtctc 26701 tgcctcgttg acaaaatgca taattctcat cggacttgtt gtacgatctt ccccgtaccg 26761 atggttactc tgggtaccag tcgccgctgt caatacctac tgctatctta gcactgactc 26821 tgagaactcg ctccgtgtgc aagttctttt agacacgttg acggcttcag actacattct 26881 cctcactgat gtccagcgcg aattccgtca ggttggacag cgagagccta tctcgagcgc 26941 tggaatctgg cctcgtttca aatgggctct ccagttatgg atttctcccc gaggagtggg 27001 gtggaacttt gagcccaagt caagtcttcc tccccatccg aatctcacca agctcgagtt 27061 tctacgatct cggttcattt cgctcgcact ggcattgatc ggcaatgata tagcatttat 27121 cctcgcctcc tctgatccag ggttctcgaa acatgcacct gcgttccaca agcagcctgt 27181 aacatggcgt ttgtatgcca ccgcgctttt ctttttcaga acgagatcgg ctctcactgt 27241 caattacctc atgatctcat tgctatgtgt cggaaccggt atgacagaac ccagttcatg 27301 gccagatcta tttggaaagt gggggcattc ttacaccctc cgtagattct gggggtcaga 27361 tggaattttt ttccatgaat aatcgcgtct ctgatcagaa cttctctctt tagggtgaca 27421 tggcatcagc agctgcgaag ggtaaattca ttccagatat ttctattata gaggcatgca 27481 ttctaatgtt gactctagat tttctcatcg cacggcagat tccttgcaca ccgcgtcttt 27541 ggctttccgt ctgggagcat tgcatcttcg tacacgcagc tttatgttgc cttcttcctc 27601 tcgagcatca ttcacgttct ttcatttgac tttcgtccgt ttcggttctt ccttttacaa 27661 gcagtagtca tcactttcga agacacgatc atcctcatag gccgtgagta ccgtgtgcag 27721 aagaagctca ccatcccctt ccggttactt ggctatttat gggtctattg gactcttact 27781 ttgactctcg ggccgtggtt cgacaccatg aatgttgcag gggttaacga atacaatggc 27841 gcctatgtcc tggggttttt acgtgactgg ttgttatcag aagattgact attgttataa 27901 ccatattcat ctgagctgta tacatcgcgg gtagatctgt atatagtact taccgtcagg 27961 cgcctctagc taacgaagat atgtacaatt ttatacgtgt taacttttaa gtcccttcct 28021 gttacatatg gacagaacag gaaccggttc tctccgtagc agtaacgcga ctttatctga 28081 cgagaaaatc tctaccattt gggaaatgct agtcgaataa agatgcctcc tatctagact 28141 tctgggtacc tttgattttt ggagtcttcg gcccgtaaag ttcggtccat gccgttgtca 28201 tgccgaagat gagacgcagc caccagtgca tgagccaggt tgaaagacgt cgaactagag 28261 ggacctcgtg tcttgacatc ctgtgtaccg cagtagaaat tctcttggtt acctaaagat 28321 atttgtcctg attcaccggt gcttgtagaa cacgcaatgg tgcaattaaa tcgcatacgg 28381 acgtgattag ttgacagacg gtcaccgtcg atgtcagata attttgggtc ttttacttcg 28441 gaaaagttca gaattcctcg gggaaagatt tgcgggtaaa ctttgagcta gacagatgat 28501 cttgttagtc ggcggaagct gaagctttca tgtcatttgc cagaatttgg ggttcgatga 28561 tctccacgtt ttgaaaactt ggcttatcac aatagttttt tttcatagac cggatctcgc 28621 gctgatacgc tggctctcta acattattat cgtaatccgt cgggtctcgg tgacagtagt 28681 gagaacagtg ggttgtgata agtggatctc agcacttatc ctagctaacc tagaaggtac 28741 ctttgtatct caatgcaagt gcaagtgagg gacatgtgat acgacattac ggagcaggtt 28801 gcagatactt tgtcaccaga ttataacgaa tagctttcac tattataaaa acgcaagatg 28861 cactatctgg acccagttta ccaccacaga gcttcactat aattatgacc gacaaagtca 28921 agatcgttcg tgactatcat gaccttctta acgcaggtca gattgcacaa gccaacgctc 28981 acttggctca caacctgacc gcaaatttct ccgttggggg gccgcagttg aacaaggagg 29041 aggttggcaa tgttcaacaa ggggttcaga atgccctgaa cactacggtc ggtggttttc 29101 tccctattct tttctttagc atttcagctc atgcttgtct ctcctagacc ctcatcaccg 29161 aagccaagga agttgatggg aaagttgtgg ttgtggtacg ttgtgattga tattagtatc 29221 atgctgtcga gtctcactaa aataattagg gcaagtcact gcttaaactc aaagtagagt 29281 acgtgaatta tttctttgag tcaggctgaa aattgacgat gcgatcctta gggaggttcc 29341 tttcaaggca gtatacgaat tcaatggcaa ccagatcggg gctgttaagt tcgagactga 29401 tcctagtttc caagtcaaag ccttcagcat ctaggtatat catgatgacc acgagttcag 29461 agaaggttgt tcaagatctg ctactctcga agttaatggc tgcatatgaa cgcgtattcg 29521 ttgtacttat atctgtacga gtcttacatg aattgttcga gttttgacat ctaagtgcat 29581 tctcaagctc ttgagtagac ctttaacgta ggtcctttaa atccttgtgt caaccaaaaa 29641 cagccgactt cgacaggcaa tctgtctaaa tatttctatc aaaagtcgag cttttattct 29701 cctttcaact tgaatgattg atctttgaca tctccgaccg actccactga ctagtcctat 29761 gtttttgtag aatataatta cactgtacac gtcatcgggc taggaccctc tccttctgaa 29821 cataactcct gctgtttggt gtgggactgc agccaacatt ccttgccatt catcaagggg 29881 gcgcacacct tctgtctcca gcttaacatc gtatgttaac agtacatgcg caagcattgt 29941 cttgagtatc gcggctacca aaaaccgtcc tggactacca aaaatggtta atttacgatg 30001 tacgacttga aaatatagct cggtgttcac catgcatgtc ttccgactcc aaataccacg 30061 tagtctgcac tgagactcgc cagttgatac cttacgggtt cattttctgc ttcgtgtttg 30121 cgaaagtgtc tgaagccatc gaattcctct ggatttgggt agtttctctt ttggcccgga 30181 gttatgggtt cgtcctgcct gattaatgca tgtccgataa aacctcaaag ccaagacaca 30241 cagacctcgt catgatggat ggagaaacca caagcgccta aagtgtttcc tgcaggaatg 30301 gtggttccat cggaaaaggt aaagtccttc ataactttgc gcgacatggt tactgaagaa 30361 atagggttag ctgaacgtaa tttggagata catttaaaag aggcaaactt ttggcgcttc 30421 catggaggcg taggctttct ttgacgaagc tatcaagttt gtacatcttg tctagaccgg 30481 ccttcgtgat aacttggccg tctaccaggg cttccacttc agaccggagt tcaggtatat 30541 aagatgactg tgctgctaag tcatatagca cttgtgtgat agcctagtaa tatgactgtg 30601 tcagacgacc tggttgaaga acatgtgcac ttacgagcga caggggacgg taggccacaa 30661 agtgtattgc cataagacgc ttagtgatgg cttcgagcga tttttcactt gctggtgctt 30721 tctccagcag ccagtttagt aggtcatcct gagactaaat caggagtttg aaattaatct 30781 taaatgatcc ataagtaaaa taacccacag tatctaattc ctcttcgccg aattgtttct 30841 gcttctcaag acgctccttc agcgttgggc caacgtgttt catcgcttcg gctaatgtat 30901 cacgataaaa gaagagcaga cgagtagcaa ggctaaattc gacgataaaa gtaagtatgt 30961 aatgctccaa gaatttgtac agaacacctc acggtttcat aactttgggt acttggctga 31021 ttatgatagc agccgtagcg agagtatctg gccaatggtc attaagagct ttatactctg 31081 ggtcacgacc taataaacca aaagaaatct ttaatgcgtt caattctcgc tcctcatgaa 31141 agtacataca taaacggaga ccaacaagca accgagtcgt tgaactgaat gcgagctgtt 31201 gccctgtaag acatcccccc agtctggtcc aatctatgtt cataaaagat tagatgaaat 31261 gaattctcta agacaattaa tgaatgataa tgctcaccat tcgtcggagg tataagctca 31321 gcaaacactg ttgctatttc atcctttatt tcagctattc ggacgccaag atctcggacg 31381 agagatgttt gtacgaattg gaagtgataa ggatcgagga gatactcggg actgaaagta 31441 tagtccgttt gcaggctcta gactcccgca gccccaataa atatgacaga agaagaaaaa 31501 ctcaacacgg gaatggtaca atgaagagag ctttacctct ttgaaaaggg cagcacgaga 31561 ggacaacccg ctctcagacg ctgctcgaac ttcctctatc atacgcggac cagtgactaa 31621 aactaaccat ccggacaaca tggggatcct aaaggccttc ccatagtgct atagggacca 31681 agtcagtaga gtaacgggtg actgaaatcg aaaacaacct tgtcgtaccc ttcctggatc 31741 aaatcgcgag tgccgaatag aaacttgtac gcccccacgt atgagtcaag taatccctct 31801 cctccgatgg ttggaatatt gagctatcac tggtgtcaaa cgatttgcgg ataagtacga 31861 atggatgata caagaccttt tgttttgact gaaatgcacg gaaaacgaca atgaagatga 31921 cgctgagagc gatacaagct gtactagtgt cgaggcacat agtgtgaaag gaaggattcg 31981 agtatcttcc acgccattag aggaaagcca tagcgcgggt attagtgatg tgtcaatcgc 32041 gatcttctca gtgaactgct gaaccattct aagctgggat tccactggga tttgctcgga 32101 ttttcgcatc atgttaagta gtccaatttt gaaattcgtc attcaatcaa ccaggtaatc 32161 agcacggata tactcatcat tcaaacactt gcacccaggt gctctttcaa gggcctgtca 32221 tgtactccat ctatctatct catgagggat gaggtgcttc gagttccatg caaggcgtca 32281 acgtgcgtca atccttttat tattgacccc gggtccggca ggccttggac cggcaagtca 32341 tcgcacgcac ggctatcccc ggtgatatcc atgtatcttt tcttgttgag gtgtgatgag 32401 cacaaccctg atgtcctctt ccacctggct cacgttagcg gtcgctctta tatccctgct 32461 cctggcccgc tccgttatcg atgagaggat cattaggtcc aaggtatgag tggtaacctc 32521 cgagcccatg tttcagttct agcaaacgca cgcatttttc tagtataaga acgttatatc 32581 tgtgggacca tcgggcatgt ttggtacctt aattggaacc ttccagctcc tgcttggata 32641 tcgagacttt attcaggagg gctatgaaaa ggtcaggtcc gtgaatactt tgacttttta 32701 gtctaacgat tttggtagca ctatggaaag ctgttcagga tcccgacttt gttcacgatg 32761 acatttgtgg tcactggtca tgatctactc gaggatgtcc gaaaagctag tgatgatcaa 32821 ctatctttat acggttctat caaagaggta cttatttagt ctttaaattc catcacaaat 32881 tcatcgcaaa gtcgtgaatc atcagggcat gcagaccgac tacacgatgg agcctcatat 32941 actcgacaat ccttatcact ttcgtttcgt tcacctctcc cttacacgcg acctaggtgg 33001 ccgttttcct gaactccggg aagaggttat aacagccttc tctgaactcg tacctccaac 33061 cgatggtaag agtttgagat catcgaaatt gaccacattt ttgtaatcaa gcatcaagat 33121 tggacctctt ttccggcctg gctcaccgga aagtctatag tactcagggt tactaataag 33181 ttatttgttg gacctccgct atgtacgttc aagctctttc gtggactcac tcttttgttc 33241 taaaatttac caacttctcg acaggtcatg acttggacta taacgacatc aatgatacat 33301 attcagacgc actcgtcaag actgcactca ttgtcggtct cacacctgat ttccttaaac 33361 cgtgcgttct tcttgtctcg tttaaaacct gagcctttac ttttattttg ttataggatc 33421 gttgccagca ctttatattt ctacatcccc aaaacgttga aacgtgcaat gaaacatgtc 33481 gccccccttg tccaagaacg acttgagaaa gagagaacat tcggcaaaga ctggccaggc 33541 aaacctgttg gttgagtatc cgttgtttga cgaccgctgt actcactcgg attgttgctc 33601 tagaatgacc ttctcagttg gctgatggag aaagcaccgg aaagcgacaa gtccgtgagg 33661 gcaatcacca ttcggctttt agcaacgatg tttgcggcgt atcgtcctgc ttctatggta 33721 ggtacatcgt tcttgtgcat gtgtatcagt gtactttctt ttgttctcta ggctctcacg 33781 caagcgttgt tcgacttggc tacatatcca tcctatatcc cagagctgcg agccgaaatc 33841 gaacctatcg tcaaagagaa agggataacc aaggagtcaa taaacaagat gtacaagctt 33901 gacagtttta tcaaggaatc gctacgtctt aggggtggtg gaaagtgtac gttgagtccg 33961 gtgtccttgt acttgttttt catctctcgt ttcatccagc aagcatgccc cgcaaggttc 34021 tcaaagactt tacgttctca gatgggaata ctgtttatac tggaagtaca ataatcgcta 34081 ctggttatgc gatacatcat gatgcagtaa gtggtttttg cttcattgac gccgaaatac 34141 gatatgaaga atgccctaca gagacattat cctgatccag atgaatttga cgggttcagg 34201 tttgctcgac taagagaggc agaaaacgac cctgttagat atcaaatggt ttcagtgggt 34261 cctacctaca tgatgttcgg gaacggaaga catgcatggt aagtgacttt tgattcctgg 34321 tgtcaggtct tgtgttaatg gatgtcactt tctctagtcc cggtcgtttc ctggtatccg 34381 cgctcttgaa gactatgctt gcgcatgtcc taatgacata tgatgttaag ctcgaacaag 34441 atgacggagt acgaccgccg gataagtggt ttacttttgc acccgctccg aatgagactg 34501 ctagtttgat gttcaggaaa agagctaatt tggcgtagtt ggctaatgtc aaatactggg 34561 tttggatggt gtgcttgatt cagtaatttc aaaagaaaag aagaaagagt tttttgtacc 34621 cattgatttc tttctagtat tgagggtgta agaataaaaa aagatcttga gacctaagca 34681 actagacaaa gtacatctac ttcaataata acagcgttag tgtgtcgggt agtacgcgtc 34741 ctgtcaaatc gacttgccat tgacgctttg tgcaacagag tgggtcacag cggggtcctc 34801 gaagacacac gcaaaaatcc aatcactttt ttgacgtgta tcttgtcaaa aagggccaca 34861 accactcacc agagccacca aacaagacac gaaagaaagt cttagagtgg gccatctttg 34921 tgcatgggga acggggcaaa accgtgggag tgtaagtaaa taaatgccgg attaaggtaa 34981 agacttgata agatcttatg atttacctca gaacggagtt tgtagaggtg acttggaggg 35041 ttactgggga ctcgaaaggt gccgttgctt actacgaggc tcactatttt gttgttcggt 35101 atgaagcaaa gttgaccacc gcaaacgtgg caagtacgag gcctgaatga gctcatcaac 35161 tgtcactggg ccgaggaagt cagactcgtc ctcggtcttg gctcgaggct tccgatgaca 35221 cacgcactcg ggtgtgtaag aagccggagt ttccgtgccc gattggtaat gaaggtcttg 35281 acaaacaaga ccacatcggt gaccaaccga ggcgaaaagt tgcgatagga cccatgctta 35341 tcctgcaaga tgtttaatcg aaagttcgga caaaaaaaat ttattttgac caaaatgttt 35401 ccccataatt cggacaaaat ggccctacag aggaaaaatg tttgacccaa aattcggaca 35461 tcatgactaa gaggtcattt aggtttgttc agagttcgga catcggctta catgagctta 35521 tattctgcca ttgttcctag tgtgtgccac agtagacagt catggataaa tatggtaata 35581 ttttgctcaa acacggtgtt cagctgtccg gctatgcctg gtctttaaat caggatcttc 35641 ttggagagcg ggccgaaatt gttggaggtg tcgtagcttt gaacaagaga cgaaggacta 35701 agaagggtat aagtgaagat gtagaggatg aagttgacaa aacctaccat tagttttacc 35761 tcattttaat tcaatcttac tttttgaagg cgtaaaaagg cctagagtac cgaataaggg 35821 cgaaaaaaaa gtggatatat gttggagcga aagttcggac aaattttttt ctgagtcgag 35881 gtcagtcccg aaattcggac agagttttag aaagggtggt tcggaaaagt tcggacaaat 35941 tttttgaaaa gtgggatttt cagatcaaac atctgatagc ataagcatgg gtcctgttgc 36001 gattcacctt ccagtcggcc tcgtgacaaa atggtctctt gaactcattg gcactacttg 36061 gtaggtgaag tgttaatttt gagatcctga attgggtcct gaacattacc acccagaagg 36121 ctttacttat ttaatattta tagtcccgtc tttgactttt ctcggcccac aggaagatgc 36181 gatttatttc ccgactttcg aaacgatttt ggctagttgc aagtttttac gagcaatcta 36241 ttcatctagt aaatcaatca aacacagtgt aaagtaatct cctcagaatt tcattttcca 36301 actttcgggt ccacattccc tagacaaaag ttgacacttt ttcaatcaaa ttttgcctgc 36361 aggttacttt acttgtctcc cgttgagggt ctgggaatcc tcgagcttca attttgagca 36421 gtggtgacac cattcccggg tttcaacggc tgctgcaaag aaactctctg catgttcacc 36481 tcaagctgca agaagaagtt gatgtctgac ccgtctccaa taaagttatt agggaatcca 36541 ggatcgagag gaacaacgtc ttcaatctct ttgatttggg taggagaaag ggaaatatcc 36601 aacgcctcga tgttttgttg ccaattctcc ggttttcgcc caccgagtac cgggaagacg 36661 taagtcgtct tctggaggag gtaagcgatg gcgactgtat gttcaatttc gctcagaaac 36721 tcaatgacag acaggtagct tgagtgaagc cagaacgtac cagcccgaat actcttcgcc 36781 tcaacctcac gcgcgatctt ctctaatgcc ctactcattg caatctcctt ctcgtttctt 36841 tcagctgcac cagggaactg tctcccatca cccttcttcc tcgcatccgc atgagccttc 36901 tcttctgagt ccgtacggag ctttcctcca gccaatacgt tccaaggcga caacgccagc 36961 ccgtgcgctc tggccatcgg gataatatct ctctcgaaag acctctccat gacgttccat 37021 gcgccttggt aaatcacaaa aggtgttttg ccggccatac gggcgtacgt attggcttca 37081 gagacgatcc atgcaggcgt atccgaaact ccctgaatac cgaccggtga tcaaacattt 37141 gaggaccgag tctgattctg atttaagtcg actcaccaaa tagataactt taccttgtgc 37201 tacaatgtta tgtagcgcat ccatgacctc ttgaacagag cagtcaaagt cccaccaatg 37261 tacatagagc aaatcgaggt aagaggttcg tagcttcttc aacgaagctt ctacggacag 37321 atgcagtgat tttgcgttat tgccaacgta ttgcactttc tgtttgacgg tggtgtcatt 37381 cttcttgtat cctgaggtgt actatgtaac aaagggtctg tgagtgggaa atattgctag 37441 gccactcaaa aagaaaagca cctttgtagc aataaagagc tgatctctga ttctcctttc 37501 ttcagcccac tttccgatga tttgctctga agtttcttct tggctattaa acccatgtag 37561 tcagcgttcg tctcaatcaa actatgcccg agatgcaatt atatcagatc tctgaaagct 37621 cactagttat tggcggtgtc aatgaagttg cctcctagtt cgtagaactt gtctaacaac 37681 cgatacgcct tggcctcgtc catgtcaccc cagacagatt tccatccact atcacctgat 37741 ccgatgcttg ctcctcccaa aacgagggga gagacacgca caccagcttt gggtgaaagg 37801 acacggtaga tgcccaactt ggatggaggg gcttcaggag gtagaaaagc ggacatggtt 37861 ggattaagag tatttgttca aggttgagtt cgtgaggagc tgagaggaaa tgggaagtaa 37921 tagataaaat cttcgggggg tatatatacc caaaaatagg taatgggttc cataactcag 37981 aaatgtgcag tgagaaatgc tttcttttcc ctgtttcttc ggtattcatt catgttggta 38041 aggtttgttt gtaaggttaa atccctacga aatcgggaat caactctaac aaacggatgg 38101 gagggacaac aatgaaaaac aagatcaata gagtttactt tctatctaat ggttaaaaga 38161 tacacaaaga caagtctcat agtaaaagag gtcacggaga cttcgatcac gatgccggat 38221 cgagccacgg aagcaaatga tggatagcct ggggtcatgc accgagagga gctgattcag 38281 aaaaacactc attggacgat tagtttattg taaagatcct caaaactctt tccattgcga 38341 atgtgtcagt ctttttgagt actacctttg tatgcaatcg agttatttct agggagcttg 38401 tgagattacg agactgaatt ctactaaact cacttgcgtt ggtggctgtg aggttttcat 38461 gtacagtgac gctgcagagt gggccatcgc tttgcgaata agtacgaggc cgttaaacaa 38521 gccgaaaggc ctttaaggtc tcggcactta cggcaatgag cctagaatgc cggcgtgaca 38581 taacatacca aataggtttg tccaacgagt ggactgaaca tcagtaagga cgagtcttcc 38641 ttaaaagtcc gagtctcc //