{
  "genotype": {
    "recessiveMode": "RECESSIVE_MODE_DISABLED",
    "sampleGenotypes": [
      {
        "sample": "CASE",
        "genotype": "GENOTYPE_CHOICE_ANY",
        "enabled": true
      }
    ]
  },
  "quality": {
    "sampleQualities": [
      {
        "sample": "CASE",
        "filterActive": true,
        "minDpHet": 10,
        "minDpHom": 5,
        "minGq": 10,
        "minAb": 0.2,
        "minAd": 3
      }
    ]
  },
  "frequency": {
    "gnomadExomes": {
      "enabled": true,
      "maxHet": 1,
      "maxHom": 0,
      "maxAf": 0.002
    },
    "gnomadGenomes": {
      "enabled": true,
      "maxHet": 1,
      "maxHom": 0,
      "maxAf": 0.002
    },
    "gnomadMtdna": {},
    "helixmtdb": {},
    "inhouse": {
      "enabled": true,
      "maxCarriers": 20
    }
  },
  "consequence": {
    "variantTypes": [
      "VARIANT_TYPE_SNV",
      "VARIANT_TYPE_INDEL",
      "VARIANT_TYPE_MNV",
      "VARIANT_TYPE_COMPLEX_SUBSTITUTION"
    ],
    "transcriptTypes": [
      "TRANSCRIPT_TYPE_CODING"
    ],
    "consequences": [
      "CONSEQUENCE_TRANSCRIPT_ABLATION",
      "CONSEQUENCE_EXON_LOSS_VARIANT",
      "CONSEQUENCE_SPLICE_ACCEPTOR_VARIANT",
      "CONSEQUENCE_SPLICE_DONOR_VARIANT",
      "CONSEQUENCE_STOP_GAINED",
      "CONSEQUENCE_FRAMESHIFT_VARIANT",
      "CONSEQUENCE_STOP_LOST",
      "CONSEQUENCE_START_LOST",
      "CONSEQUENCE_TRANSCRIPT_AMPLIFICATION",
      "CONSEQUENCE_DISRUPTIVE_INFRAME_INSERTION",
      "CONSEQUENCE_DISRUPTIVE_INFRAME_DELETION",
      "CONSEQUENCE_CONSERVATIVE_INFRAME_INSERTION",
      "CONSEQUENCE_CONSERVATIVE_INFRAME_DELETION",
      "CONSEQUENCE_MISSENSE_VARIANT",
      "CONSEQUENCE_SPLICE_DONOR_FIFTH_BASE_VARIANT",
      "CONSEQUENCE_SPLICE_REGION_VARIANT",
      "CONSEQUENCE_SPLICE_DONOR_REGION_VARIANT",
      "CONSEQUENCE_SPLICE_POLYPYRIMIDINE_TRACT_VARIANT"
    ]
  },
  "locus": {},
  "clinvar": {}
}